Table 2. Efficiency of CMAH targeting using fibroblast cells with isogenic CMAH profile as the reference sequence. No difference was found in the efficiency of targeting in male and female cells.
Source of cells | No. of cells transfected | No. of neo-positive colonies | No. of positive colonies (%) |
---|---|---|---|
Male | 2 × 106 | 13 | 5 (38.4) |
Female | 2 × 106 | 23 | 10 (43.5) |
Total | 36 | 15 (41.7) |