Table 3.

Healthcare Expenditures, by Index Cohort

Total healthcare expenditures	All patients (N = 2272)		Patients who received temozolomide only (N = 89)		Patients who received radiation therapy only (N = 313)		Patients who received temozolomide and radiation therapy (N = 841)		Patients who did not receive temozolomide or radiation therapy (N = 1029)
	Mean, $	SD, $	Mean, $	SD, $	Mean, $	SD, $	Mean, $	SD, $	Mean, $	SD, $
Expenditures in the 6 months preindex surgery
Total healthcare expenditures	11,949	17,609	12,850	15,636	11,564	17,550	12,320	19,873	11,686	15,735
Total inpatient	5368	14,133	6108	11,833	5265	13,835	6403	16,225	4490	12,424
Total outpatient	5548	7288	5873	8122	5207	6660	5005	7857	6067	6874
Emergency department	346	1299	283	579	237	649	361	1394	373	1407
Outpatient, hospital	2748	5231	2838	6020	2414	3859	2533	5799	3019	5021
Outpatient, office visits	547	463	417	471	539	444	451	396	639	499
Other outpatient	1906	3726	2335	4586	2016	4111	1661	3828	2036	3418
Total retail/mail-order pharmacy expenditures (all drugs)	1034	1578	869	1177	1093	1528	912	1242	1129	1840
Antiemetics	4	52	1	4	10	87	4	43	4	46
Cancer therapies	0	0	0	0	0	0	0	0	0	0
Neutropenia-related	3	146	0	0	0	0	0	0	7	217
Painkillers	35	253	24	76	32	141	27	231	43	302
Expenditures in the 6 months postindex surgery
Total healthcare expenditures	106,896	97,678	111,066	108,664	111,456	84,701	138,767	76,627	79,099	107,140
Total inpatient	61,423	81,688	72,041	50	56,634	67,477	59,121	57,768	63,843	98,632
Total outpatient	36,109	38,660	22,895	25,786	52,063	39,975	58,860	37,701	13,804	24,174
Emergency department	525	1643	523	915	507	1239	680	1668	403	1767
Outpatient, hospital	21,602	32,426	13,488	21,868	30,963	36,302	38,047	38,144	6016	14,008
Outpatient, office visits	831	1039	1052	1937	901	1309	1211	1084	479	578
Other outpatient	13,151	22,518	7832	12,280	19,691	25,540	18,923	25,266	6905	17,490
Total retail/mail-order pharmacy expenditures (all drugs)	9364	11,323	16,130	9479	2759	3840	20,786	9590	1452	3046
Antiemetics	431	1110	549	862	400	1266	905	1453	44	335
Cancer therapies	7057	9757	13,555	7710	586	2100	17,204	8116	170	1396
Neutropenia-related	38	532	19	179	31	411	71	747	16	337
Painkillers	43	161	36	145	52	168	42	125	40	185
Expenditures in the 12 months postindex surgery
Total healthcare expenditures	131,815	121,379	134,512	115,938	131,869	101,065	184,107	112,929	88,827	117,423
Total inpatient	68,645	90,003	74,465	102,251	63,385	73,947	71,487	73,371	67,419	104,511
Total outpatient	49,212	58,986	35,427	43,706	63,124	48,980	82,750	68,286	18,763	32,572
Emergency department	732	1943	815	1421	723	1583	965	2032	538	1988
Outpatient, hospital	29,128	48,770	18,110	28,083	38,082	45,189	52,060	64,125	8615	17,910
Outpatient, office visits	1306	1567	1547	2564	1363	1724	1883	1782	796	911
Other outpatient	18,046	30,249	14,955	29,688	22,956	27,190	27,841	36,118	8814	21,993
Total retail/mail-order pharmacy expenditures (all drugs)	13,957	17,723	24,621	19,657	5360	8504	29,870	17,173	2645	5502
Antiemetics	575	1495	715	1158	578	1892	1190	1911	59	421
Cancer therapies	10,059	14,915	20,349	14,691	1529	5482	23,962	14,533	402	2905
Neutropenia-related	96	1296	249	1694	84	1312	181	1856	16	337
Painkillers	78	380	49	212	87	316	89	424	68	371

SD indicates standard deviation.