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. 2014 Jun;4(2):269–279. doi: 10.1086/675990

Figure 1.

Figure 1

Expression and localization of erythropoietin (EPO) is increased in pulmonary arterial hypertension lung tissue. EPO is highly expressed in smooth muscle cells and endothelial cells of arteries showing muscular hypertrophy and plexiform lesions. EPO is also localized in alveolar epithelial cells. Inflammatory cells show positive staining for EPO in pulmonary arterial hypertension (PAH). IPAH: idiopathic PAH; NIPAH: nonidiopathic PAH. Scale bar: 80 μm.