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. 2014 Jun;4(2):289–299. doi: 10.1086/675992

Figure 6.

Figure 6

Rho kinase–mediated vasoconstriction is increased by Schistosoma (Schisto) exposure. A, Optical density (OD) of guanosine triphosphate (GTP)-bound (active) RhoA in whole-lung protein lysates; n = 5–6 animals/group; t test: P = 0.02. B–D, Right ventricular systolic pressure (RVSP) in SU5416 (SU)-treated mice with or without concurrent Schistosoma exposure recorded before (B) and 5 minutes after (C) fasduil administration and the decrease in pressure for each animal (D); n = 8–9 animals/group. In all panels, an asterisk indicates P < 0.05 by t test.