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. 2013 Sep;3(3):675–691. doi: 10.1086/674440

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© 2013 by the Pulmonary Vascular Research Institute. All rights reserved.

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Asymmetric dimethylarginine (ADMA) regulates c-jun expression and phosphorylation. C-jun expression (A), c-jun phosphorylation (B), and connexin 43 (Cx43; C) expression in untreated human pulmonary artery endothelial cells (HPAECs) and HPAECs treated with ADMA, SP600125, mock transfected (OligofectAMINE only), transfected with nontargeting small interfering RNA (siRNA) or c-jun siRNA, or overexpressing DDAHI (AdDDAHI), as indicated. D, Representative Western blots corresponding to A–C. One asterisk: ; two asterisks: ; three asterisks: , comparisons with transfection controls.

Inline graphic — Asymmetric dimethylarginine (ADMA) regulates c-jun expression and phosphorylation. C-jun expression (A), c-jun phosphorylation (B), and connexin 43 (Cx43; C) expression in untreated human pulmonary artery endothelial cells (HPAECs) and HPAECs treated with ADMA, SP600125, mock transfected (OligofectAMINE only), transfected with nontargeting small interfering RNA (siRNA) or c-jun siRNA, or overexpressing DDAHI (AdDDAHI), as indicated. D, Representative Western blots corresponding to A–C. One asterisk: ; two asterisks: ; three asterisks: , comparisons with transfection controls.