Figure 1.

A, 4-aminopyridine (4-AP; 10⁻³ M)-induced change in membrane potential (Em) for arteries from normoxic () and hypoxic () piglets from the 10-day exposure group. An asterisk indicates significant difference from normoxia (). B, 4-AP-induced changes in diameter for endothelium-intact and air-infused arteries from normoxic and hypoxic piglets from the 10-day exposure group (for normoxic arteries, intact arteries and air-infused arteries; for hypoxic arteries, intact arteries and air-infused arteries). An asterisk indicates significant difference from normoxic intact arteries, and a plus sign (B) indicates significant difference from normoxic air-infused arteries (). In both panels, values are mean ± SEM.