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. 2013 Sep;3(3):551–563. doi: 10.1086/674307

Figure 2.

Figure 2

A, Effect of treatment with the superoxide dismutase mimetic M40403 and the H2O2-decomposing agent polyethylene glycol catalase (PEG-CAT) on responses to 4-aminopyridine (4-AP) in arteries from normoxic and hypoxic piglets of the 10-day exposure group (for normoxic arteries: Inline graphic untreated arteries and Inline graphic M40403+PEG-CAT-treated arteries; for hypoxic arteries: Inline graphic untreated arteries and Inline graphic M40403+PEG-CAT-treated arteries). B, Effect of treatment with the NADPH oxidase inhibitor apocynin on responses to 4-AP in arteries from normoxic and hypoxic piglets of the 10-day exposure group (for normoxic arteries: Inline graphic untreated arteries and Inline graphic apocynin-treated arteries; for hypoxic arteries: Inline graphic for untreated arteries and Inline graphic apocynin treated arteries). In both panels, values are mean ± SEM, an asterisk indicates a significant difference from untreated normoxic arteries, and a plus sign indicates a significant difference from untreated hypoxic arteries (Inline graphic).