Table 1.

Pretransplant echocardiography

Date	RVSP, mmHg	RVFAC, %	TAPSE, cm	TR maximum velocity, m/s	Myocardial performance index	Diastole EI	Therapy
Nov 14, 2007	65	52	2.2	3.9	0.33	1.12
Jan 15, 2008	111	59	2.3	5.3	0.29	1.36
Jan 16, 2008a	43			3.3			Started sildenafil
Jan 28, 2010	55	39	3.3	3.8	0.23	1.30	Sildenafil and bosentan
Feb 27, 2010b	115	73	2.7	4.6	0.08	1.51
Feb 27, 2010c	85	…	…	…	…	…	Sildenafil, bosentan; started inhaled treprostinil
Sep 1, 2010	93	66	2.3	4.8	0.08	1.41
Oct 8, 2010	61	65	2.5	3.9	0.07	1.46	Sildenafil, bosentan, and IV treprostinil
May 17, 2011	NA	62	2.9	NA	0.07	1.28	Posttransplant

^NoteEarly echocardiographic (echo) data (2007–2008) demonstrate evidence of pulmonary arterial hypertension (PAH) with preserved right ventricular (RV) systolic function. Later echo data (2010) demonstrate worsening PAH with increasing eccentricity index (EI) during diastole, suggestive of flattening of the interventricular septum due to RV volume overload. Echo at 3 months after transplant (May 2011) shows resolution of patient’s EI during diastole, consistent with resolution of PAH. RVSP: RV systolic pressure; RVFAC: RV fractional area change; TAPSE: tricuspid annulus peak systolic excursion; TR: tricuspid regurgitant; NA: could not estimate.

^aInhaled NO study.

^bBefore inhaled prostacyclin.

^cAfter inhaled prostacyclin.