FIG. 2.

Mean serum LH levels in female WT and Kiss1r KO mice exposed to a positive feedback regimen of low E₂ followed by an injection of EB to induce rising E₂. The day after EB injection, blood was collected from mice at either a morning (1000 h) or an evening (lights off; 1800 h) time point. *Significantly different from all other groups (P < 0.01). All data are expressed as the mean ± SEM for each group.