Table 2. CpG Loci significantly associated with IUS exposure in CAMP asthmatics (N = 527).
| Probe ID | Symbol | Chr | Mean methylation level | β* | Difference in methylation** | FDR p-value |
| cg05697249 | C11orf52 | 11 | 0.66 | 0.09 | 0.02 | 0.001 |
| cg14724265 | PPEF2 | 4 | 0.76 | 0.17 | 0.03 | 0.01 |
| cg25464840 | FRMD4A | 10 | 0.75 | 0.13 | 0.02 | 0.01 |
| cg20588045 | PCDH15 | 10 | 0.28 | 0.10 | 0.02 | 0.01 |
| cg20555507 | TRPM3 | 9 | 0.08 | 0.13 | 0.01 | 0.03 |
| cg16184943 | ZNF280B | 22 | 0.34 | −0.09 | −0.02 | 0.03 |
| cg09352789 | XPNPEP1 | 10 | 0.29 | −0.06 | −0.01 | 0.03 |
| cg07499072 | FST | 5 | 0.04 | 0.11 | 0.004 | 0.03 |
| cg22830895 | CRYGN | 7 | 0.43 | 0.11 | 0.03 | 0.03 |
| cg13473383 | ZDHHC5 | 11 | 0.09 | −0.08 | −0.01 | 0.03 |
| cg10556064 | SMPD3 | 16 | 0.58 | 0.10 | 0.02 | 0.03 |
| cg04112019 | IGF2AS | 11 | 0.12 | 0.07 | 0.01 | 0.03 |
| cg00169548 | BAZ1A | 14 | 0.48 | −0.10 | −0.02 | 0.03 |
| cg10493739 | TMEM38B | 9 | 0.06 | −0.07 | −0.004 | 0.03 |
| cg01058368 | CDH10 | 5 | 0.82 | 0.12 | 0.02 | 0.04 |
| cg09143663 | BACH1 | 21 | 0.72 | 0.08 | 0.02 | 0.04 |
| cg20773127 | ENPEP | 4 | 0.58 | 0.10 | 0.02 | 0.05 |
| cg24956866 | CALD1 | 7 | 0.58 | 0.10 | 0.02 | 0.05 |
| cg14580737 | RFXANK | 19 | 0.80 | −0.10 | −0.02 | 0.05 |
* coefficient from beta regression adjusted for age, sex, and clinic and cell type.
**coefficient from linear regression model illustrating difference in methylation level comparing IUS exposed to unexposed.