Table 3. CISH genotype and allelic frequencies for association with persistent HBV infection in Chinese Han population.
SNPs | Case (n = 594) | Control(n = 425) | OR(95%CI) | x2 | adjusted p value |
rs2239751 | |||||
GG | 78 (13.13%) | 75 (17.65%) | 1 | 6.01 | 0.05 |
GT | 277 (46.63%) | 201 (47.29%) | 1.39 (0.95–2.02) | 2.92 | 0.09 |
TT | 239 (40.24%) | 149 (35.06%) | 1.63(1.10–2.39) | 5.99 | 0.01 |
G | 433(36.45%) | 351(41.29%) | 1 | ||
T | 755(63.55%) | 499(58.70%) | 1.23(1.02–1.47) | 4.92 | 0.03 |
rs414171 | |||||
AA | 107(18.01%) | 101(23.76%) | 1 | 8.40 | 0.02 |
TA | 283(47.64%) | 204(48.00%) | 1.39(0.99–1.99) | 3.67 | 0.06 |
TT | 204(34.34%) | 120(28.24%) | 1.71(1.19–2.47) | 8.40 | 0.004 |
Allele A | 497(41.83%) | 406(47.76%) | 1 | ||
Allele T | 691(58.16%) | 444(52.24% | 1.27(1.07–1.52) | 7.06 | 0.01 |
rs622502 | |||||
GG | 529(89.06%) | 372(87.53%) | 1 | 1.13 | 0.57 |
GC | 62 (10.43%) | 50 (11.76%) | 1.30(0.242–6.70) | 0.09 | 0.76 |
CC | 3 (0.51%) | 3 (0.71%) | 1.58(0.31–8.17) | 0.30 | 0.59 |
G | 1120(94.28%) | 794(93.41%) | 1 | ||
C | 68(5.72%) | 56(6.59%) | 1.16(0.81–1.67) | 0.65 | 0.42 |
rs6768300 | |||||
CC | 532(89.56%) | 373(87.76%) | 1 | 2.32 | 0.31 |
GC | 61 (10.27%) | 49 (11.53%) | 0.82 (0.55–1.24) | 0.86 | 0.35 |
GG | 1 (0.17%) | 3 (0.71%) | 0.24 (0.02–2.37) | 1.51 | 0.22 |
C | 1125(94.70%) | 795(93.53%) | 1 | ||
G | 63(5.30%) | 55(6.47%) | 1.24(0.85–1.79) | 1.24 | 0.27 |
Data were calculated by binary logistic regression analysis.