Table 4. Genotype and allelic distribution for CISH gene polymorphisms when AsC group was compared to CHB+LC group.
SNP | AsC (N = 240) | CHB+LC (N = 354) | OR(95%CI) | x2 | adjusted P value |
rs2239751 | |||||
GG | 37(15.42%) | 41(11.58%) | 1 | 2.06 | 0.36 |
GT | 102(42.50%) | 175(49.44%) | 1.47(0.86–2.51) | 2.01 | 0.16 |
TT | 101(42.08%) | 138 (38.98%) | 1.29 (0.75–2.22) | 0.86 | 2.51 |
G | 176(36.67%) | 257(36.30%) | 1 | ||
T | 304(63.33%) | 451(63.70%) | 0.98(0.774–1.25) | 0.02 | 0.90 |
rs414171 | |||||
AA | 50(20.83%) | 57 (16.10%) | 1 | 2.32 | 0.31 |
AT | 104(43.33%) | 179 (50.56%) | 1.45 (1.90–2.33) | 2.32 | 0.13 |
TT | 86(35.83%) | 118 (33.33%) | 1.31(0.80–2.16) | 1.13 | 0.30 |
A | 204(42.50%) | 293(41.38%) | 1 | ||
T | 276(57.50%) | 415(58.62%) | 0.96(0.76–1.21) | 0.15 | 0.70 |