Table 1.
Association of nestin expression with clinicopathological features in ESCC
| Characteristics | No. of patients |
Nestin expression
n
(%) |
P -value * | ||
|---|---|---|---|---|---|
| Positive | Negative | ||||
| Gender |
Male |
72 |
24 (33.3) |
48 (66.7) |
0.686 |
| |
Female |
21 |
8 (38.1) |
13 (61.9) |
|
| Age (y) |
≤60 |
51 |
16 (31.4) |
35 (68.6) |
0.497 |
| |
>60 |
42 |
16 (38.1) |
26 (61.9) |
|
| Differentiation |
Poor |
32 |
6 (18.7) |
26 (81.3) |
0.070 |
| |
Moderate |
44 |
19 (43.2) |
25 (56.8) |
|
| |
Well |
17 |
7 (41.2) |
10 (58.8) |
|
| TNM stage |
I |
5 |
1 (20) |
4 (80) |
0.133 |
| |
II |
56 |
23 (41.1) |
33 (58.9) |
|
| |
III + IV |
32 |
9 (30.8) |
23 (69.2) |
|
| Lymph nodes |
Positive |
34 |
9 (26.5) |
25 (73.5) |
0.221 |
| |
Negative |
59 |
23 (39.0) |
36 (61.0) |
|
| Ki67 expression |
Positive |
53 |
23 (43.4) |
30 (56.6) |
0.036 |
| |
Negative |
40 |
9 (22.5) |
31 (77.5) |
|
| PCNA expression |
Positive |
56 |
26 (46.4) |
30 (53.6) |
0.003 |
| |
Negative |
37 |
6 (16.2) |
31 (83.8) |
|
| CDK5 expression |
Positive |
50 |
23 (46.0) |
27 (54.0) |
0.022 |
| |
Negative |
43 |
10 (23.3) |
33 (76.7) |
|
| P35 expression |
Positive |
45 |
24 (53.3) |
21 (46.7) |
0.031 |
| Negative | 48 | 15 (31.2) | 33 (68.8) | ||
*Chi-square test.