Table 2.
Univariate and multivariate analyses of nestin expression in relation to median survival time of ESCC patients
| Variable |
Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Nestin expression |
|
|
|
|
|
|
| Positive |
1.579 |
1.025–2.432 |
0.038 |
1.586 |
1.007–2.499 |
0.047 |
| Negative |
1.000 |
|
|
1.000 |
|
|
| Differentiation |
|
|
|
|
|
|
| Poor |
0.680 |
0.442–1.049 |
0.081 |
0.658 |
0.412–1.053 |
0.080 |
| Moderate and well |
1.000 |
|
|
1.000 |
|
|
| TNM classification |
|
|
|
|
|
|
| III + IV |
1.268 |
0.820–1.961 |
0.286 |
0.862 |
0.201–3.692 |
0.842 |
| I + II |
1.000 |
|
|
1.000 |
|
|
| Sex |
|
|
|
|
|
|
| Male |
1.181 |
0.716–1.946 |
0.515 |
1.397 |
0.826–2.363 |
0.212 |
| Female |
1.000 |
|
|
1.000 |
|
|
| Age |
|
|
|
|
|
|
| ≥60 years |
0.881 |
0.582–1.334 |
0.550 |
0.755 |
0.486–1.172 |
0.210 |
| <60 years |
1.000 |
|
|
1.000 |
|
|
| Lymph nodes metastasis |
|
|
|
|
|
|
| With |
1.330 |
0.864–2.048 |
0.195 |
1.870 |
0.451–7.757 |
0.388 |
| Without | 1.000 | 1.000 | ||||
Abbreviations:HR hazard ratio; LN lymph nodes.
*Chi-square test.