Table 1. Characteristics of the patient groups^a.

Variables	Control (n = 8)	T2DM (n = 12)	P-value
Age (range, median)	48–86, 69.9	52–82, 69.4	0.729
Sex (M/F)	6/2	8/4	1
Islet cell count (/cm2)b
alpha	3576±681.5	1800±389.9	0.017
beta	5401±965.5	2246±398.1	0.014
total	15069±2983.0	7571±1126.1	0.043
% Islet cells with CADM1 cell-membranous stainingb
alpha	49.5±2.19	13.6±3.53	<0.001
beta	81.3±1.24	22.3±6.16	<0.001
HbA1c (%)b , c	5.8±0.23	7.3±0.25	0.007
(mmol/mol)	(39.7±2.33)	(56.4±2.75)

^aData for individual patients are presented in Table S1.

^bData are expressed as the mean ± SE.

^cControl, n = 3; T2DM, n = 10.