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Summary diagram of differentially expressed gene results obtained from a microarray study of human RPE cell response to in vitro stimulation with amyloid beta (0.3 μM, left oval) or advanced glycation endproducts (AGE, 10 μg/mL, right oval). Amyloid beta and AGE are two known components of drusen, and results suggest that both induce proinflammatory responses, including IFN-γ signaling.
