Figure 10. lin-28^dF30 Abnormal Egg Chambers Exhibit Impaired Fas2 Expression Pattern, which is Necessary during Oogenesis.

(A) While Fas2 expression was confined to the polar cells in lin-28^dF30/+ stage 8 egg chamber (asterisk), all (n = 38) the lin-28^dF30 stage 8 abnormal egg chambers displayed an extended anterior expression domain (arrows). (B) Abrupt has a pivotal role during oogenesis, taking part in GSC differentiation and regulating BC migration. The proposed network could explain the various defects observed in the lin-28^dF30 ovaries. Scale bar represent 25 µm.