. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Radiat Res. 2014 Mar 27;181(4):350–361. doi: 10.1667/RR13567.1

TABLE 2.

Identification of Urinary Biomarkers at ~6 h after Irradiation with 1.25 Gy

Marker no.	Retention time (min)	ESI mode	Mass (m/z) found	Predicted	ppm error	Empirical formula	Identity	K-S P value
1	5.11	positive	310.2017	310.1993	7.74	C₁₅H₂₉NO₄	l-Octanoylcarnitine + Na	0.0003
2	0.35	positive	137.0457	137.0463	4.38	C₅H₄N₄O	Hypoxanthine	0.0006
3	0.26	positive	189.1586	189.1602	8.46	C₉H₂₀N₂O₂	N6,N6,N6-Trimethyl-l-lysine	0.008
4	0.36	positive	204.1243	204.1235	3.92	C₉H₁₇NO₄	Acetyl-dl-carnitine	0.01
5	5.43	positive	338.2332	338.2306	7.69	C₁₇H₃₃NO₄	Decanoylcarnitine + Na	0.01
6	0.34	negative	167.0202	167.0205	1.80	C₅H₄N₄O₃	Uric acid	0.001
7	0.34	negative	151.0246	151.0256	6.62	C₅H₄N₄O₂	Xanthine	0.02

Notes. Markers that exhibited statistical significance through the Kolmogorov-Smirnov test when pre-exposure vs. 6 h post-exposure data were compared. Pathways affected include energy metabolism with implications for fatty acid oxidation, and purine catabolism potentially affecting the purine salvage pathway.