Fig. 6.

(A) Maximal contractile response (E-max) induced by phenylephrine (PE). (B) Effective concentration 50 (EC50) of PE. (C) Relaxant responses to acetylcholine (Ach) in the endothelium-intact aortic rings of control rats, PTZ treated rats, PTZ+LTG and LTG treated rats. PTZ (pentylenetetrazole, 30mg/kg), LTG (lamotrigine, 20 mg/kg).Data are expressed as mean±SD, number of animals=7. ^#p<0.05 compared to control group, ^*p<0.05 compared to PTZ group by analysis of variance (ANOVA), followed by Newman-Keuls multiple comparison test.