Figure 1.
Schematic structures of KIT and PDGFR. The percentages indicate the frequency of mutations detected in each exon of the gene that encodes for the protein.
From Joensuu H, DeMatteo RP. The management of gastrointestinal stromal tumors: a model for targeted and multidisciplinary therapy of malignancy. Annu Rev Med. 2012;63:247–258; with permission.