Table 2.

Temporal trends in the annual percent change (APC) in age-adjusted papillary thyroid cancer incidence rates between 1988 and 2009 in California, by individual and tumor characteristics.

	Trend 1		Trend 2		Trend 3		Trend 4		Trend 5
	years	APC	years	APC	years	APC	years	APC	years	APC
	Men
All	1988–1998	1.1 (−0.3–2.5)	1998–2009	5.4 (4.5–6.3)
Age
<20	1988–2009	1.3 (−1.4–4.1)
20–34	1988–2009	2.6 (1.8–3.4)
35–49	1988–1996	−2.1 (−5.8-1.8)	1996–2009	4.9 (3.4–6.5)
50–64	1988–2009	4.3 (3.6–5.0)
≥65	1988–2009	4.6 (3.6–5.6)
Race/ethnicity/nativity
non-Hispanic white	1988–1995	−0.4 (−3.2-2.4)	1995–2009	5.4 (4.6–6.3)
non-Hispanic black	1988–2009	4.1 (2.3–6.1)
Hispanic	1988–2009	3.9 (2.5–5.2)
US-born	1988–2004a	3.3 (0.4–6.2)
foreign-born	1988–2004a	2.2 (−1.7–6.3)
Asian/Pacific Islander	1988–2006	1.1 (−0.3–2.5)	2006–2009	16.8 (2.3–33.5)
US-bornb	1988–2004a	2.9 (−2.4–8.5)
foreign-bornb	1988–2004a	−0.2 (−2.3-1.9)
Native Americanc	--
Tumor size
<1 cm	1988–2009	7.8 (6.9–8.8)
1.0–1.4 cm	1988–2009	5.7 (4.5–7.0)
1.5–1.9 cm	1988–1993	−7.1 (−17.2-4.3)	1993–2009	8.1 (6.5–9.8)
2.0–2.9 cm	1988–2009	4.0 (3.1–4.9)
3.0–3.9 cm	1988–2009	3.5 (2.2–4.9)
4.0–4.9 cm	1988–2009	3.6 (2.4–4.8)
≥5.0 cm	1988–2009	4.4 (3.3–5.6)
unknown	1988–1997	−11.5 (−14.0- -9.0)	1997–2009	−2.2 (−4.3-0.0)
SEER stage
local	1988–1995	−0.6 (−4.3-3.2)	1995–2009	5.5 (4.5–6.5)
regional	1988–2003	1.5 (0.1–2.8)	2003–2009	10.2 (5.9–14.6)
distant	1988–2009	1.5 (−0.1–3.1)
unknown	1988–2009	−1.9 (−4.5-0.8)
Tumor size / stage
<2.0 cm / local	1988–2009	7.8 (7.0–8.6)
<2.0 cm / advancedd	1988–2009	5.8 (5.0–6.6)
≥2.0 cm / local	1988–2009	3.2 (2.2–4.2)
≥2.0 cm / advanced	1988–2009	4.8 (3.9–5.6)
unknown/local	1988–2009	−9.9 (−12.3- -7.5)
unknown/advanced	1988–2000	−10.5 (−13.8- -7.2)	2000–2009	3.1 (−3.4– 10.0)
	Women
All	1988–2001	3.8 (3.4–4.2)	2001–2009	6.3 (5.7–6.9)
Age
<20	1988–2009	2.1 (0.6–3.7)
20–34	1988–2009	3.0 (2.6–3.5)
35–49	1988–2001	3.9 (3.2–4.6)	2001–2009	6.1 (5.1–7.2)
50–64	1988–1992	7.3 (2.7–12.1)	1992–1995	−0.6 (−12.3–12.6)	1995–1999	9.3 (3.5–15.5)	1999–2003	4.6 (0.2–9.3)	2003–2009	8.4 (7.2–9.6)
≥65	1988–2009	6.0 (5.3–6.7)
Race/ethnicity
non-Hispanic white	1988–1993	1.6 (−0.7–3.8)	1993–2009	5.4 (5.1–5.8)
non-Hispanic black	1988–2009	5.3 (3.8–6.8)
Hispanic	1988–2009	4.8 (4.3–5.2)
US-born	1988–2004a	4.7 (3.2–6.2)
foreign-born	1988–2004a	4.0 (2.6–5.5)
Asian/Pacific Islander	1988–2003	2.2 (1.3–3.1)	2003–2009	7.1 (4.8–9.5)
US-bornb	1988–2004a	4.1 (2.3–6.0)
foreign-bornb	1988–2004a	1.1 (0.1–2.1)
Native Americanc	1988–2009	4.4 (0.9–8.0)
Tumor size
<1 cm	1988–2009	9.0 (8.5–9.5)
1.0–1.4 cm	1988–2004	6.3 (5.7–6.8)	2004–2009	12.1 (10.0–14.3)
1.5–1.9 cm	1988–2009	5.2 (4.5–5.9)
2.0–2.9 cm	1988–2009	3.8 (3.4–4.2)
3.0–3.9 cm	1988–1994	8.5 (4.1–13.2)	1994–2009	3.6 (2.8–4.4)
4.0–4.9 cm	1988–1995	10.5 (5.1–16.2)	1995–2009	4.0 (2.8–5.1)
≥5.0 cm	1988–2009	5.0 (4.0–6.0)
unknown	1988–1995	−9.7 (−12.4- -6.8)	1995–2009	−5.1 (−6.5- -3.7)
SEER stage
local	1988–1998	3.4 (2.5–4.3)	1998–2009	6.0 (5.4–6.6)
regional	1988–2000	2.9 (1.6–4.1)	2000–2009	8.2 (6.8–9.6)
distant	1988–1998	9.3 (4.9–13.9)	1998–2009	−2.9 (−5.6- -0.1)
unknown	1988–1995	11.3 (−0.3–24.2)	1995–2009	−7.3 (−11.3- -3.2)
Tumor size / stage
<2.0 cm / local	1988–2009	7.8 (7.5–8.1)
<2.0 cm / advancedd	1988–2005	6.2 (5.2–7.2)	2005–2009	14.9 (9.2–20.8)
≥2.0 cm / local	1988–2005	3.8 (3.3–4.4)	2005–2009	−0.1 (−4.0–4.1)
≥2.0 cm / advanced	1988–2009	5.6 (5.0–6.2)
unknown/local	1988–1991	−5.8 (−14.8-4.3)	1991–1994	−22.0 (−38.1- -1.7)	1994–2009	−4.5 (−5.7- -3.1)
unknown/advanced	1988–2009	−6.6 (−8.1- -5.0)

^anativity data can only be calculated for the period 1988–2004

^bincludes Chinese, Japanese, Filipino, Vietnamese, Korean, and South Asian persons

^cAmerican Indian/Alaskan Native

^dcombines regional and distant stages