| Immune |
|
|
|
|
|
| CD177 |
197.49 |
19.186 |
10.29 |
0.01215 |
A glycosylphosphatidylinositol (GPI)-anchored membrane protein is a potential receptor for PR3, the preferred target of antineutrophil cytoplasmic antibodies (ANCAs) in Wegener's granulomatosis. Involved in neutrophil transmigration. |
| IFI27 |
4643.67 |
1503.71 |
3.09 |
0.0256 |
Mediates IFN-induced apoptosis |
| IRF9 |
293.777 |
45.0231 |
6.53 |
0.0048 |
Transcription regulatory factor that mediates type I interferons |
| LENG9 |
1209.33 |
73.0508 |
16.55 |
0.00145 |
Negative regulators of macrophage activation |
| LCP2 |
86.2228 |
24.4284 |
3.53 |
0.0378 |
SLP76, a substrate for T cell ZAP70, promotes T cell development |
| Cellular Function |
|
|
|
|
|
| ABCC5 |
122.498 |
20.6639 |
5.93 |
0.00545 |
ATP binding cassette transporter |
| ATP5B |
162.509 |
41.1475 |
3.95 |
0.01605 |
ATP synthase |
| BNIP2 |
44.0329 |
7.76199 |
5.67 |
0.0191 |
bcl-2 binding protein, responsive to estrogen; regulates cell dynamics by interacting with cdc42 |
| CDKN2B |
243.227 |
86.5265 |
2.81 |
0.02475 |
Cyclin dependent kinase inhibitor, controls cell cycle G1 progression |
| DYNLL1 |
528.599 |
129.298 |
4.09 |
0.01345 |
Intracellular transport and motility |
| ESRRA |
435.007 |
83.0017 |
5.24 |
0.01245 |
Estrogen receptor related alpha, cell growth and maintenance |
| INSR |
49.2393 |
14.5811 |
3.38 |
0.00755 |
Insulin receptor, regulates cell growth |
| KREMEN2 |
63.2595 |
0 |
NA |
0.0284 |
Receptor for Dickkopf protein, cooperates with Dickkopf to block Wnt signaling. |
| MLLT4 |
53.2364 |
14.4052 |
3.70 |
0.0059 |
Organization of cell junctions, belongs to the cell adhesion system |
| MTRNR2L6 |
340.597 |
36.8941 |
9.23 |
0.00025 |
Antiapoptotic factor |
| PDPK1 |
54.8395 |
9.62117 |
5.70 |
0.0045 |
Master lipid kinase regulating PI-3 kinase pathway/Akt, apical endosome trafficking |
| RAP2A |
81.8369 |
29.7633 |
2.75 |
0.0357 |
Belongs to the ras oncogene family, regulates cytoskeletal rearrangements |
| SCNN1A |
132.419 |
16.8286 |
7.87 |
0.0077 |
Sodium mediated non voltage ion channel. Mediates diffusion of luminal sodium and water through the apical membrane |
| SP3 |
56.516 |
21.7481 |
2.60 |
0.0271 |
A transcription factor that can be regulated by acetylation, e.g., SCFA, can repress insulin like growth factor action. |
| TRIM36 |
50.8464 |
5.88888 |
8.63 |
0.0004 |
Mediates ubiquitination and proteosomal degradation; chromosome segregation and cell cycle regulation |
