Table 1. Characteristics of Patients in General and Separately in SVR, Relapse and Non-Response Groups a,b.
Total (n = 139) | SVR (n = 50), 35.97% | Relapse (n = 50), 35.97% | No. Resp. (n = 39), 28.05% | P Value | |
---|---|---|---|---|---|
Host factors | |||||
Age, y | 39.87 (12.53) | 40.14 | 39.94 | 39.43 | 0.965 |
BMI, kg/m2 | 23.98 (4.96) | 23.75 | 23.84 | 24.43 | 0.795 |
Gender | |||||
Male | 109 (78.41) | 42 (84) | 40 (80) | 27 (69.23) | 0.234 |
Female | 30 (21.58) | 8 (16) | 10 (20) | 12 (30.76) | |
IL28b | |||||
CC | 44 (31.65) | 19 (38) | 19 (38) | 6 (15.38) | |
CT | 68 (48.92) | 24 (48) | 25 (50) | 19 (48.71) | 0.002 |
TT | 27 (19.42) | 7 (14) | 6 (12) | 14 (35.89) | |
WBC, cells/µL | 8479.06 (6666.48) | 6684.4 | 9232.8 | 9813.58 | 0.053 |
Hb, g/dL | 13.86 (2.71) | 15.46 | 13.09 | 12.81 | <0.0001 |
Plt, L/μL | 318418.70 (870807.41) | 208080 | 271860 | 519569.23 | 0.221 |
FBS, mg/dL | 98.89 | 94.68 | 96.1 | 107.87 | 0.14 |
TG, mg/dL | 119.27 (52.58) | 124.32 | 112.41 | 121.61 | 0.503 |
Chol, mg/dL | 144.28 (41.23) | 161.48 | 134.22 | 135.15 | 0.001 |
PT (s) | 13.10 (1.17) | 12.88 | 13.28 | 13.15 | 0.227 |
Total Biopsy Score | 9.47 (4.43) | 9 | 9.48 | 10.07 | 0.531 |
AST/ALT | 0.87 (0.36) | 0.8 | 0.91 | 0.91 | 0.254 |
Viral factors | |||||
Viral Load, IU/mL | 1406288.4 (3362429.25) | 1590823.24 | 1000116.36 | 1690438.69 | 0.564 |
Genotype | |||||
1a | 95 (68.34) | 33 (66) | 34 (68) | 28 (71.79) | 0.776 |
1b | 20 (14.38) | 9 (18) | 6 (12) | 5 (12.82) | |
3a | 22 (15.82) | 8 (16) | 8 (16) | 6 (15.38) | |
4a | 2 (1.43) | 0 | 2 (4) | 0 |
a Abbreviations: ALT; alanine transaminase, AST; aspartate transaminase, BMI; body mass index, Chol; cholesterol, FBS; fasting blood sugar, Hb; hemoglobin, Plt; platelet, PT; prothrombin time, TG; triglyceride, WBC; white blood cell.
b Data are presented as No. (%).