Skip to main content
. 2014 Jun 9;124(7):3147–3158. doi: 10.1172/JCI75429

Figure 7. Negative associations between baseline immune activation and YF-17D vaccine response.

Figure 7

(A) Negative correlation between the frequency of CD38+ CD21+ CD27– B cells at baseline and the YF-17D NAb titers in both cohorts. (B) Negative correlation between the frequency of tissue-like memory B cells at baseline and the YF-17D NAb titers in both cohorts. (C) Negative correlation between the expression level of PD-1 on memory CD8 T cells at baseline and the YF-17D NAb titers in both cohorts. (D) Negative correlation between the frequency of CD14+ CD16+ monocytes at baseline and the YF-17D NAb titers in both cohorts. Black dots represent data points from the Entebbe cohort, and white dots represent data points from the Lausanne cohort. (E) Negative correlation between the IL-10 secretion in the supernatant of PBMCs at baseline stimulated for 24 hours with YF-17D and the NAb titers in the Entebbe cohort. (F) Negative correlation between the absolute monocyte count at baseline and the YF-17D NAb titers in the Entebbe cohort.