Table 1.

Comparison of histological parameters in the quadriceps muscles of A/J mice and double-deficient mice at 6–8 months of age

Measurement	A/J (n =3)	Double-deficient (n =4)	p-value
Total number of fibres per field	99.290 ± 4.375	82.720 ± 3.572	0.0059
Regenerating fibres per field	0.071 ± 0.071	0.444 ± 0.232	0.1791
Fibres with central nuclei per field	8.714 ± 1.447	11.610 ± 1.547	0.1921
Peripheral nuclei per fibre	1.453 ± 0.041	1.480 ± 0.059	0.7326
Central nuclei per fibre	0.107 ± 0.017	0.185 ± 0.028	0.0371
Total nuclei per fibre	1.561 ± 0.043	1.664 ± 0.067	0.2312
Ratio of central to peripheral nuclei per fibre	0.075 ± 0.012	0.126 ± 0.019	0.0362
Number of inflammatory foci per muscle*	34.000 ± 4.509	25.500 ± 6.185	0.3492

^*A group of ten inflammatory cells was considered as one inflammatory foci.