Fig. 5.

Effect of cordycepin on interleukin-1β (IL-1β)-induced activation of nuclear factor kappa B (NF-κB) in IL-1β-stimulated human osteoarthritis (OA) chondrocytes pretreated with cordycepin at 10, 50 or 100 μM for 2 h and then stimulated or not with IL-1β (5 ng/ml) for 1 h. Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IκB-α) degradation and phosphorylation and nuclear factor kappa B (NF-κB) p65 activation were analysed by Western blotting