Table 2.

Cytotoxic evaluation for compounds 1–12.

Compound	IC50 (nM) or% Inhibition a
	PC3	NFF
1	34.2	123
2	2180	5650
3	2870	39% at 10 μM
4	2.20	8.16
5	11.0	70.6
6	31.7	188
7	381	1190
8	0.0484	0.404
9	0.269	1.03
10	33.1	99.1
11	118	425
12	155	708
Taxol	2.26	3.94
Doxorubicin	359	530

^a Each IC₅₀ (nM) or % inhibition at 10 μM was determined as the mean of two independent experiments with triplicate determinations for each concentration.