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. 2014 Jun 5;12(6):3416–3448. doi: 10.3390/md12063416

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

(a) Principal component score plot analysis of 77 strains clustered according to features (m/z ratios) from mass spectral data (R₂ = 0.4). Bioactivities of outliers are represented using symbols; (*) Anti-trypanosomal activity against Trypanosoma brucei brucei, (•) PTP1B, (Δ) TRPV1, (◊) TRPA1, (□) TRPM8, (○) PPARα, and (▪) Enterococcus faecalis. Rhodococcus sp. ZS402 was also found to be NRPS positive (+); (b) Accompanying PCA loading plot of the 77 strains investigated in this study; (c) Variable intensity plot illustrating two metabolites observed as outliers in (b) (m/z 265.1476 and m/z in 279.1631) in Rhodococcus sp. ZS402.