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. 2014 Jun 19;15:207. doi: 10.1186/1471-2105-15-207

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Copyright © 2014 Videm et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Distribution of fold-change values (log₂of light: heavy ratios) for the proteomic analysis of a murine BMDC membrane fraction comparing wild-type cells to SPPL2a^-/-SPPL2b^-/-cells. (a) all identified proteins, (b) membrane-spanning proteins, (c) cytoplasmic domains of membrane-spanning proteins, (d) non-cytoplasmic domains of membrane-spanning proteins (e.g. extracellular, lumenal).