Table 1.

Amino acid sequence similarity between particular γ-secretase subunits in various species based on PSI-BLAST analyses. Sequences from Homo sapiens (Hs) were used as reference sequence (query)

	HsPS1	HsPS2	HsPEN-2	HsAPH-1	HsNCT
A. thaliana	42.6%	44.4%	35.3%	42.0%	38.1%
P. patens	42.5%	39.3%	39.3%	39.0%	39.9%
C. reinhardtii	38.5%	37.0%	38.0%	40.4%	31.1%
D. discoideum	42.2%	42.5%	55.7%	37.2%	37.6%