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. 2014 Jun 11;2014:670506. doi: 10.1155/2014/670506

Figure 2.

Figure 2

Antigen-specific IgG antibody responses in BALB/c mice vaccinated with a single dose of EV71 inactivated virus formulated with different adjuvant. BALB/c mice (N = 6) were i.m. vaccinated with 0.2 μg of inactivated EV71 virus alone or formulated with Alum or PELC emulsified particles. At week 8, serum samples were collected from blood and the antibodies were measured by ELISA; the reactivity of neutralization epitope VP1211–225 or VP2136–150 was determined by peptide ELISA. The data were presented as GMTs with standard errors of six mice per group. *P < 0.05: comparison with the group without adjuvant. # P < 0.05: comparison with the group of Alum adjuvant.