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. 2014 Jun 11;2014:651872. doi: 10.1155/2014/651872

Figure 4.

Figure 4

Correlation of cytokines levels and circulating CXCR5+CD4+ TFH cells in EV71-infected patients including mild and severe cases. (a) Cytokines levels of IL-21 and IL-6 in sera from HC and EV71-infected patients. (b) Relationship between the IL-21 levels and the frequency of circulating CXCR5+CD4+ TFH cells. (c) Relationship between the IL-6 levels and the frequency of circulating CXCR5+CD4+ TFH cells. (d) Relationship between the IL-6 levels and IL-21 levels. Data shown were the mean ± SD. The horizontal lines show the median. *P < 0.05; **P < 0.01; ***P < 0.001; ns.: no significant difference.