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. 2014 Jun 26;8:234. doi: 10.3389/fnbeh.2014.00234

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Copyright © 2014 Wu, Bai, Tan, Li, Xia, Chang, Zhou, Zhou, Li, Wang, and Dong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lithium reduces repetitive self-grooming behavior in neonatal isolation rats. The time spent in grooming is strongly increased in isolated rats during test, and lithium treatment restores the excessive grooming behavior to normal level. Two-way ANOVA analysis was used in this experiment. For repetitive self-grooming time: treatment × drug, F_{(1, 135)} = 4.214, P < 0.05; treatment, F_{(1, 135)} = 6.008, P < 0.05; drug, F_{(1, 135)} = 6.191, P < 0.05. Data show mean ± SEM (*p < 0.05; **p < 0.01).