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. 2014 Jun 26;8:234. doi: 10.3389/fnbeh.2014.00234

Figure 4.

Figure 4

Lithium reduces neonatal isolation-induced anxiety-like behavior in the novelty-suppressed feeding test. The feeding latency (A) is significantly increased; while the amount of food intake (B) is significantly reduced in isolated rats compared to control. Lithium treatment reinstates this behavior. (C) No differences are observed in total food consumption including during test and in home cage among these groups. Two-way ANOVA analysis was used in this experiment. For latency to intake: treatment × drug, F(1, 74) = 3.064, P > 0.05; treatment, F(1, 74) = 6.901, P < 0.05; drug, F(1, 74) = 1.900, P > 0.05. For food intake during test: treatment × drug, F(1, 74) = 2.608, P > 0.05; treatment, F(1, 74) = 5.022, P < 0.05; drug, F(1, 74) = 1.946, P > 0.05. For total food intake: treatment × drug, F(1, 74) = 0.405, P > 0.05; treatment, F(1, 74) = 0.001, P > 0.05; drug, F(1, 74) = 1.941, P > 0.05. Data show mean ± SEM (*p < 0.05; **p < 0.01).