Table 5.
Distribution of XRCC3 rs1799796 genotype among ovarian cancer cases and controls included in the meta-analysis.
| First author | Year |
Genotypes distribution (Case source) |
Genotypes distribution (Controls source) |
P-HWE (Controls) |
T2T2 versus T1T1 | T1T2 versus T1T1 | T1T2+T2T2 versus T1T1 | T2T2 versus T1T1+T1T2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T1T1 | T1T2 | T2T2 | T1T1 | T1T2 | T2T2 | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
| Auranen [20] | 2005 | 769 | 692 | 203 | 1757 | 1776 | 433 | Yes | 1.07 [0.89, 1.29] | 0.47 | 0.89 [0.79, 1.01] | 0.062 | 0.93 [0.83, 1.04] | 0.188 | 1.13 [0.95, 1.35] | 0.17 |
| Quaye [25] | 2009 | 676 | 608 | 177 | 1040 | 1006 | 253 | Yes | 1.08 [0.87, 1.33] | 0.5 | 0.93 [0.81, 1.07] | 0.31 | 0.96 [0.84, 1.09] | 0.536 | 1.11 [0.91, 1.37] | 0.30 |
|
| ||||||||||||||||
| Total | 1445 | 1300 | 380 | 2797 | 2782 | 686 | 1.07 [0.93, 1.24] | 0.33 | 0.91 [0.83, 0.99] | 0.04 | 0.94 [0.86, 1.03] | 0.16 | 1.13 [0.98, 1.29] | 0.08 | ||
|
Test for
heterogeneity |
P = 0.97 |
Test for
heterogeneity |
P = 0.65 |
Test for
heterogeneity |
P = 0.69 |
Test for
heterogeneity |
P = 0.90 | |||||||||