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Pharmacokinetics and biodistribution of 3H-labeled PEGylated liposomes versus HA-liposomes (with varying MW of HA) after a single iv bolus injection into CD-1 mice. At different time points, mice were sacrificed; residual blood radioactivity of 3H-liposomes is presented as %ID remaining in total blood (A). The radioactivity in various organs at 24 h (B) postinjection is presented as %ID/g. All values are reported as mean ± SD (n = 3–6 mice per time point).
