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. 2014 Jun 26;10(6):e1004414. doi: 10.1371/journal.pgen.1004414

Figure 4. Exome sequencing analysis of KCL-22M vs KCL-22 cells.

Figure 4

(A, B) Chromosomal distribution of point mutation (A) and indel (B) hot spots identified specifically in KCL-22M cells. The counts of point mutation or indel events in 1 Mb windows along each chromosome were drawn. (C) Venn diagram analysis of significant gene expression probe sets from Figure 1A, point mutations and indels in coding exons. The numbers included 160 annotated probes from the 245 expression probe sets, 194 unique genes for a total of 208 point mutations in coding exons, and 56 accession numbers for a total of 33 unique genes bearing frame-shift indels in coding exons. None of 7 overlapping genes were on chromosome 4.