Table 1. Type I collagen post-translational hydroxylation.

	Hyl/(Hyl+Lys)	4-Hyp/(Hyp+Pro)	% α2(I) P707 3-Hyp	% α1(I) P986 3-Hyp	% Telo Hyl (NH2, COOH)
+/+
fibroblast	20.0±1.5	49.5±1.3	<10	97	ND
skin	12.9±1.2	40.2±2.2	6–10	80	ND
osteoblast	46.4±1.8	50.9±1.5	24	97	ND
femur	ND	ND	13–21	98	85, 85
humerus	24.8±3.2	45.4±1.2	ND	ND	ND
+/−
fibroblast	21.7±0.8	48.5±0.9	<10	>89	ND
skin	12.8±0.3	39.8±0.8	6–11	80	ND
osteoblast	ND	ND	24	97	ND
femur	ND	ND	10–12	98	ND
humerus	30.1±0.2	46.1±1.4	ND	ND	ND
−/−
fibroblast	20.1±1.0	51.2±1.2	<10	11	ND
skin	2.5±1.9	41.9±1.4	1–2	2	ND
osteoblast	43.7±0.8	52.7±1.5	13	5	ND
femur	ND	ND	5–7	2	95, 83
humerus	30.8±3.4	45.1±1.1	ND	ND	ND

ND, Not determined.