Skip to main content
. 2014 Jun 26;9(6):e98648. doi: 10.1371/journal.pone.0098648

Figure 1. Contaminating LPS increases airway resistance to OVA following metacholine challenge.

Figure 1

(a) Lung resistance in LPS-rich and LPS-free OVA challenged mice 48 hours following three OVA challenges, LPS rich OVA increased Lung resistance. (b) Lung elastance compared to saline control in both LPS-rich and LPS-free OVA challenged mice as per (a). Mice were sensitized with OVA on day 0 and 7 and challenged intra-nasally with either LPS-free or LPS-rich OVA on day 14, 15, 16 and assessed for lung mechanics on day 18. * OVA-LPS rich vs. PBS, + OVA-LPS free vs. PBS, # OVA-LPS free vs. OVA-LPS rich. Number of symbols denotes signficance, e.g, *** = P<0.001, Values are shown as Mean ± SEM, N = 8. Statistical significance was determined using ANOVA.