Table 3. The two variants that can't be excluded.

		Variations			Bioinformation prediction			Variations in
Family ID	Gene	Nucleotide	Amino acid	Status	Polyphen-2	SIFT	Splice	patients	controls	Note
Family 1	CRYBA4	c.26C>T	p.A9V	Hetero	Benign	Tolerate	/	1/18	0/96	Novel
Family 5	GJA8	c.367G>A	p.G123S	Hetero	Benign	Tolerate	/	1/18	0/96	COSM1333689

Note: Hetero = heterozygosity.