Table 2. Association of SNPs in ADIPOR1 with T2D, CAD and T2D with CAD in additive genetic model.

SNPs	Risk allele	Additive model	T2D+CAD vs. Control		CAD vs. Control		T2D vs. Control
			OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
rs7539542	G	GG vs. GC vs. CC	1.24(0.83–1.85)	0.295	1.38(0.94–2.05)	0.104	0.97(0.69–1.36)	0.838
rs3737884	G	GG vs. GA vs. AA	2.42(1.51–3.89)	2.48×10−4 *	2.42(1.55–3.77)	9.80×10−5 *	1.96(1.33–2.89)	6.30×10−4 *
rs1342387	A	AA vs. AG vs. GG	1.09(0.72–1.67)	0.679	1.12(0.76–1.65)	0.568	1.12(0.79–1.57)	0.529
rs16850797	C	CC vs. CG vs. GG	1.71(1.11–2.62)	0.014*	1.21(0.79–1.87)	0.380	1.77(1.17–2.67)	0.007*
rs12045862	T	TT vs. TC vs. CC	1.07(0.69–1.67)	0.760	1.11(0.75–1.63)	0.614	1.32(0.92–1.90)	0.130
rs7514221	C	CC vs. CT vs. TT	1.68(0.90–3.15)	0.105	1.98(1.11–3.52)	0.021	1.73(1.02–2.96)	0.043

SNPs, single nucleotide polymorphisms; CAD, coronary artery disease; T2D, type 2 diabetes; T2D+CAD, T2D with CAD; OR, odds ratios; CI, confidence interval. All OR and P values are obtained by unconditional logistic regression and adjusted for gender, age and body mass index The df of a per-allele OR value is 2 in the additive genetic model analysis. All variants with nominal significance (P≤0.05) are listed; the threshold for significance by Bonferroni correction is 0.05/3 = 0.017 (three independent hypotheses: T2D vs. Control, CAD vs. Control, T2D with CAD vs. Control).

*P value that can pass Bonferron correction (P≤0.017).