Table 3. PD patients and control subjects with and without REM-related SDB.
| PD patients | Control subjects | |||||
| REM-relatedSDB | not REM-relatedSDB | p | REM-related-SDB | not REM-relatedSDB | p | |
| (n = 11) | (n = 38) | (n = 20) | (n = 34) | |||
| Sex, male | 6 (55%) | 28 (74%) | 0.20 | 14 (70%) | 25 (74%) | 0.51 |
| Age, y | 63±10 | 66±7 | 0.38 | 61±7 | 66±7 | 0.02 |
| BMI, kg/m2 | 30.2±6.1 | 26.1±3.7 | 0.05 | 28.2±3.6 | 28.5±5.7 | 0.79 |
| SAS-SDQ-score | 31.6±6.7 | 34.8±6.9 | 0.20 | 38.4±6.7 | 38.8±6.8 | 0.83 |
| ESS | 6.2±2.4 | 11.5±5.1 | <0.001 | 12.3±5.7 | 10.7±4.6 | 0.31 |
| ESS≥10 | 1 (9%) | 23 (62%) | 0.002 | 15 (75%) | 19/32 (59%) | 0.20 |
| Disease duration, y | 6.1±5.0 | 10.5±7.2 | 0.03 | |||
| UPDRS III | 22.4±7.4 | 27.4±13.4 | 0.12 | |||
| RBD | 6 (55%) | 29 (81%) | 0.09 | |||
| Total sleep, min | 363±51 | 331±59 | 0.09 | 350±59 | 373±51 | 0.15 |
| Sleep latency to NREM2, min | 33.8±21.6 | 23.5±19.5 | 0.14 | 21.8±19.1 | 28.0±30.5 | 0.36 |
| Arousal index, /h | 6.6±5.7 | 10.7±8.0 | 0.07 | 15.1±10.9 | 22.8±13.2 | 0.03 |
| Sleep efficiency, % | 81.8±8.7 | 76.5±12.0 | 0.12 | 81.1±12.8 | 83.2±11.6 | 0.55 |
| Wake, % | 17.7±9.1 | 23.4±12.0 | 0.11 | 18.9±12.8 | 15.0±7.9 | 0.23 |
| REM, % | 15.5±5.3 | 15.0±7.0 | 0.79 | 12.3±5.7 | 12.2±4.4 | 0.95 |
| NREM1, % | 12.2±5.3 | 13.7±9.8 | 0.91 | 14.8±10.4 | 21.4±14.1 | 0.06 |
| NREM2, % | 42.7±9.6 | 36.4±11.4 | 0.08 | 36.8±10.2 | 37.3±10.0 | 0.85 |
| SWS, % | 11.8±8.2 | 11.6±8.1 | 0.93 | 17.3±6.2 | 13.6±7.3 | 0.05 |
| Apnea-hypopjnea index, /h | 12.0±4.2 | 24.8±18.4 | 0.06 | 15.9±7.9 | 26.2±16.5 | 0.02 |
| Apnea index, /h | 2.7±2.2 | 17.5±15.9 | <0.001 | 10.0±6.5 | 17.4±14.1 | 0.09 |
| Obstructive apnea index, /h | 2.3±2.2 | 9.5±12.0 | 0.01 | 8.9±5.9 | 10.4±10.3 | 0.78 |
| Central apnea index, /h | 0.2±0.3 | 4.2±7.5 | 0.13 | 0.3±0.5 | 3.4±7.8 | 0.37 |
| Mixed apneaindex, /h | 0.2±0.2 | 4.0±7.7 | 0.004 | 0.8±1.1 | 3.4±4.4 | 0.01 |
| Hypopnea index, /h | 9.3±4.2 | 7.3±5.9 | 0.23 | 6.0±4.1 | 9.0±7.7 | 0.19 |
BMI: body mass index; ESS: Epworth Sleepiness Scale; NREM: non-REM; RBD: REM sleep behavior disorder; REM: rapid eye movement; SaO2: oxygen saturation; SAS-SDQ: Sleep Apnea scale of the Sleep Disorders Questionnaire; SDB: sleep-disordered breathing; SWS: slow wave sleep UPDRS: Unified Parkinson’s Disease Rating Scale.