Table 1. Case-control studies of Prothrombin 20120 G-A Polymorphism and All Preeclampsia.
study | country | ethnicity | cases | controls | OR | 95%CI | ||
GG | GA/AA | GG | GA/AA | |||||
De Groot(1999) | Netherland | Caucasian | 158 | 5 | 157 | 6 | 0.83 | (0.25–2.77) |
Kupferminc(2000) | Israel | Caucasian | 73 | 7 | 151 | 5 | 2.90 | (0.90–9.44) |
Higgins(2000) | Australia | Caucasian | 134 | 5 | 116 | 3 | 1.44 | (0.34–6.17) |
D’Elia(2002) | Italy | Caucasian | 57 | 1 | 73 | 1 | 1.28 | (0.08–20.92) |
Morrison(2002) | Scotland | Caucasian | 396 | 4 | 164 | 0 | 3.73 | (0.20–69.74) |
Prochazk(2003) | Czech | Caucasian | 37 | 1 | 50 | 0 | 4.04 | (0.16–102.0) |
Fabbro(2003) | Italy | Caucasian | 50 | 2 | 78 | 2 | 1.56 | (0.21–11.43) |
Driul(2005) | Italy | Caucasian | 38 | 1 | 63 | 1 | 1.66 | (0.10–27.29) |
Mello(2005) | Italy | Caucasian | 386 | 16 | 397 | 5 | 3.29 | (1.19–9.07) |
Demir(2006) | Turkey | Caucasian | 65 | 5 | 95 | 7 | 1.04 | (0.32–3.43) |
Yalinkaya(2006) | Turkey | Caucasian | 96 | 4 | 98 | 2 | 2.04 | (0.36–11.41) |
Hiltunen(2009) | Finland | Caucasian | 244 | 4 | 673 | 6 | 1.84 | (0.52–6.57) |
Best(2009) | US | American Indian | 86 | 1 | 164 | 1 | 1.91 | (0.12–30.86) |
Kahn(2009) | Canada | Caucasian | 110 | 3 | 435 | 8 | 1.48 | (0.39–5.68) |
Seremak-Mrozikiewicz(2010) | Poland | Caucasian | 104 | 5 | 395 | 5 | 3.80 | (1.08–13.37) |
Malek-Khosravi(2012) | Western Iran | Caucasian | 194 | 4 | 98 | 3 | 0.67 | (0.15–3.07) |
Pooled(M-H) | 1.81 | (1.25–2.63) |
Q = 8.10, p = 0.920, I2 = 0.0%.