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A, Apoptotic cells were detected in-diabetic (NDM) Ren2 rats (a & b), diabetic (DM) Ren2 rats treated with vehicle (c & d), and aliskiren (e & f). ONL: outer nuclear layer; INL: inner nuclear layer; RGC: retinal ganglion cell layer. B, Quantitative measurement of apoptotic cells detected by TUNEL assay. #p<0.01 (vs. wildtype (WT) Sprague–Dawley rats); $p<0.01 (vs. NDM Ren2 and WT); *p<0.01 (vs. NDM Ren2 and DM Ren2+ vehicle).
