Table 3. Gene categories enriched among down-regulated and up-regulated genes in low KPY samples.

GO category	Meunna			Florentine
	Totalgenes	Changedgenes	FDR	Totalgenes	Changedgenes	FDR
Down-regulated
GO:0006793_phosphorus_metabolic_process	337	81	0.00	318	91	0.00
GO:0006796_phosphate_metabolic_process	337	81	0.00	318	91	0.00
GO:0005975_carbohydrate_metabolic_process	201	54	0.00	181	57	0.00
GO:0016310_phosphorylation	316	78	0.00	300	86	0.01
GO:0006468_protein_phosphorylation	307	77	0.00	291	85	0.01
GO:0008361_regulation_of_cell_size	34	14	0.01	33	15	0.01
GO:0016049_cell_growth	34	14	0.01	33	15	0.01
GO:0032535_regulation_of_cellular_component_size	34	14	0.01	33	15	0.01
GO:0090066_regulation_of_anatomical_structure_size	34	14	0.01	33	15	0.01
GO:0033036_macromolecule_localization	137	37	0.01	136	46	0.00
GO:0006464_protein_modification_process	420	93	0.01	393	104	0.00
GO:0009825_multidimensional_cell_growth	9	6	0.01	7	5	0.05
GO:0040007_growth	45	17	0.01	42	17	0.01
GO:0015031_protein_transport	102	29	0.01	100	33	0.02
GO:0045184_establishment_of_protein_localization	102	29	0.01	100	33	0.02
GO:0008104_protein_localization	108	30	0.01	106	34	0.01
GO:0007167_enzyme_linked_receptor_protein_signaling_pathway	27	11	0.02	27	12	0.03
GO:0007169_transmembrane_receptor_protein_tyrosine_kinase_signaling_pathway	27	11	0.02	27	12	0.03
GO:0043412_macromolecule_modification	461	96	0.03	432	107	0.01
GO:0023033_signaling_pathway	121	32	0.03	118	35	0.03
GO:0048869_cellular_developmental_process	56	18	0.03	55	19	0.05
GO:0051234_establishment_of_localization	310	68	0.03	289	77	0.02
GO:0000902_cell_morphogenesis	29	11	0.04	29	12	0.05
GO:0051179_localization	319	69	0.05	298	78	0.01
GO:0006810_transport	309	67	0.05	288	76	0.01
GO:0007264_small_GTPase_mediated_signal_transduction	38	13	0.05	40	15	0.05
Up-regulated
GO:0006950_response_to_stress	385	81	0.00	345	103	0.00
GO:0006952_defense_response	156	48	0.00	128	45	0.00
GO:0050896_response_to_stimulus	592	107	0.00	546	140	0.00
GO:0009628_response_to_abiotic_stimulus	97	32	0.00	178	54	0.02
GO:0006915_apoptosis	83	31	0.00	71	25	0.05

FDR – Fisher’s exact p value corrected for multiple comparisons.