Figure 5. Effect of free and encapsulated bisphosphonates on Balb/C mouse macrophage cultures.
Count of adherent and non-adherent macrophages by Trypan Blue staining after 1, 2 and 6 days after removal of drugs. Results are mean ±SD of 3 experiments. CTL = controls; UL = unloaded RBCs; L-Zol = RBCs loaded with Zoledronate to a final concentration of 7.0±1.89 µmoles/ml of packed RBCs. **p<0.01 by ANOVA analysis with Bonferroni post-hoc test.