Table 3. Cell density in corpus striatum.
Stained region per High Power Field (HPF) | Mn mine workers n=8 | Non-Mn mine workers n=8 | % difference | p value |
---|---|---|---|---|
Astrocytes caudate | 9.85 ± 3.94 | 12.86 ± 3.90 | 23% ↓ | 0.146 |
Astrocytes putamen | 8.91 ± 3.64 | 11.63 ± 2.97 | 23% ↓ | 0.125 |
Astrocytes GPe | 12.80 ± 3.68 | 12.40 ± 3.64 | 0.846 | |
Astrocytes GPi | 10.60 ± 2.66 | 10.60 ± 3.64 | 0.979 | |
Microglia caudate | 1.25 ± 0.30 | 1.18 ± 1.01 | 0.856 | |
Microglia putamen | 1.29 ± 0.50 | 1.24 ± 0.60 | 0.859 | |
Microglia GPe | 1.33 ± 0.55 | 0.87 ± 0.34 | 53% ↑ | 0.064 |
Microglia GPi | 1.37 ± 0.75 | 0.99 ± 0.49 | 38% ↑ | 0.250 |
Neurons caudate | 16.50 ± 6.79 | 19.90 ± 3.72 | 17% ↓ | 0.235 |
Neurons putamen | 16.00 ± 7.16 | 18.10 ± 3.30 | 11% ↓ | 0.455 |
Neurons GPe | 1.87 ± 0.86 | 1.34 ± 0.52 | 40% ↑ | 0.162 |
Neurons GPi | 2.05 ± 0.81* | 1.28 ± 0.39 | 60% ↑ | 0.028* |
p<0.05, two tailed t-test; GPe=globus pallidus external segment; GPi=globus pallidus internal segment