Figure 1. PCR validation of miRNA microarray results.

qRT-PCR analysis of miR-146a, miR-21 and miR-155 expression normalized to 5S rRNA from B. burgdorferi-infected joints of B6, C3H and IL10^−/− mice at 1, 2, or 4 weeks post-infection (n = 3–4). Shown is fold change in expression compared to uninfected controls ± SEM. * indicates statistically significant increase in expression vs. uninfected controls by ANOVA followed by Dunnett's post-hoc test, α = 0.05.