Table 3. mRNA expression of induced cytokines in BMDMs from B6 and B6 miR-146a^−/− mice after 6 and 24 hours stimulation with B. burgdorferi.

Strain	6 hours			24 hours
	IL1β	IL6	TNFα	IL1β	IL6	TNFα
B6	56.2±2.5	0.008±0.002	127.3±6.6	109.7±12.7	1.07±0.46	6.42±0.58
miR-146a−/−	236±8.7	0.06±0.007	168.2±14.7	446.8±14.0	2.67±0.35	7.91±0.37
Fold Δ	4.2	7.5	1.3	4.1	2.5	1.2

Induced transcript levels of IL1β, IL6 and TNFα (normalized to 1000 β-actin) in B6 and B6 miR-146a^−/− BMDMs stimulated with B. burgdorferi for 6 or 24 hours. Data shown are mean±SE, as well as fold difference (Fold Δ) of expression in miR-146a^−/− vs. B6. Transcript levels of uninfected cells were very low and similar between strains (not shown). Representative of 3 independent experiments (n≥3 for each experiment).