Table 3.
Proportion of carriers of *T allele of PTPN22 in relation to the presence of the adenosine deaminase locus 2 *2 allele of adenosine deaminase locus 2 polymorphism
Proportion of carriers of *T allele of PTPN22 | Total of subjects, n | ||
Non diabetic subjects with CAD | |||
ADA2 *1/*1 genotype | 8.3% | 84 | |
Carriers of ADA2 *2 allele | 20.8% | 48 | |
Non diabetic subjects with cardiovascular diseases without CAD | |||
ADA2 *1/*1 genotype | 6.7% | 75 | |
Carriers of ADA2 *2 allele | 2.2% | 46 | |
Blood donors | |||
ADA2 *1/*1 genotype | 4.5% | 88 | |
Carriers of ADA2 *2 allele | 5.1% | 59 | |
Statistical analysis | χ2 test of independence | ||
χ2 | df | P | |
ADA2 *1/*1 genotype | 1.024 | 2 | 0.599 |
Carriers of ADA2 *2 allele | 11.747 | 2 | 0.003 |
CAD: Coronary artery disease; ADA2: Adenosine deaminase locus 2.